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Notably, the 23andMe data did not reveal an association with BMI or weight, indicating that the association of the SNP may be identifiable more strongly in the context of GLP1 treatment

To test whether the mean DNA methylation level at CYP2E1 was different between the two groups of acetaminophen detection, we fit linear regression models using R/Bioconductor package limma [32] for each of the 28 candidate CpG sites